Self-assembled nano-photosensitizer for cancer phototheranostics

Self-assembled nano-photosensitizer for targeted, activatable, and biosafe cancer phototheranostics

This study develops a GSH-activated, cancer-targeting nano-photosensitizer (MBNPs) based on methylene blue. MBNPs enable precise, effective, and safe photodynamic therapy (PDT) guided by fluorescence and photoacoustic imaging. This all-in-one platform shows strong potential for future clinical cancer treatment.

November 2022 · Ke Cheng#, Junyang Qi#, Jie Zhang, Huangxu Li, Xiaojie Ren, Wenyu Wei, Lingkuan Meng, Jing Li, Qianqian Li, Huatang Zhang, Wenbin Deng, Hongyan Sun, Lin Mei